Circulating microRNA: a new candidate for diagnostic biomarker in neuroblastoma
نویسندگان
چکیده
منابع مشابه
Circulating microRNA-196a as a candidate diagnostic biomarker for chronic hepatitis C
Previous studies have demonstrated the inhibitory effect of microRNA (miR)-196a on hepatitis C virus (HCV) expression in human hepatocytes. However, the clinical implications of aberrant miR-196a expression and the application of circulating miR-196a in the diagnosis and management of chronic hepatitis C (CHC) require further investigation. The present study aimed to examine the possibility of ...
متن کاملState of the art in circulating miR-95 as a new candidate for diagnostic in Human Chronic Lymphocytic Leukemia
Backgrounds: MicroRNAs (miRNAs) have crucial roles in cellular and molecular processes related to different malignancies including chronic lymphocytic leukemia (CLL). In recent years the most studies demonstrated that the expression of miR-95, alter in several diseases. Long non-coding RNAs (lncRNAs) a heterogeneous group of non-coding and regulatory RNAs. The present study investigated the as...
متن کاملMicroRNA-206: A Potential Circulating Biomarker Candidate for Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a lethal motor neuron disease that progressively debilitates neuronal cells that control voluntary muscle activity. Biomarkers are urgently needed to facilitate ALS diagnosis and prognosis, and as indicators of therapeutic response in clinical trials. microRNAs (miRNAs), small posttranscriptional modifiers of gene expression, are frequently altered in dise...
متن کاملCirculating miR-132-3p as a Candidate Diagnostic Biomarker for Malignant Mesothelioma
The use of circulating microRNAs as biomarkers has opened new opportunities for diagnosis of cancer because microRNAs exhibit tumor-specific expression profiles. The aim of this study was the identification of circulating microRNAs in human plasma as potential biomarkers for the diagnosis of malignant mesothelioma. For discovery, TaqMan Low Density Array Human MicroRNA Cards were used to analyz...
متن کاملCirculating MicroRNA-21 Is a Potential Diagnostic Biomarker in Gastric Cancer
MicroRNA-21 was upexpressed in gastric cancer (GC) indicating that it is a potential diagnostic biomarker for GC. In this study, 50 GC patients and 50 healthy controls were recruited. miR-21 levels in serum and peripheral blood mononuclear cells (PBMCs) were quantified using quantitative real-time PCR. CA199, and CEA were measured using electrochemiluminescence assay. The sensitivity and specif...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cancer Gene Therapy
سال: 2016
ISSN: 0929-1903,1476-5500
DOI: 10.1038/cgt.2016.45